We have performed a longitudinal study of the content of the putative neurotransmitter substances, enkephalin, dynorphin, and acetylcholine (ACh), in the cochlea of the Fischer 344 rat. It is the first study of transmitters in the rat cochlea over an extended time span. This study also provides biochemical verification of the presence of ACh in cochlear tissues. No change was seen in the cochlear content of these transmitter candidates up to 24 months of age.
Peer Reviewed
http://deepblue.lib.umich.edu/bitstream/2027.42/27136/1/0000129.pdf