Sangam: A Confluence of Knowledge Streams

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

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dc.contributor University of Aberdeen.Data Safe Haven
dc.contributor University of Aberdeen.Institute of Medical Sciences
dc.contributor University of Aberdeen.Applied Medicine
dc.contributor University of Aberdeen.Clinical Medicine
dc.contributor University of Aberdeen.Aberdeen Biomedical Imaging Centre
dc.creator Howard, David M.
dc.creator Hall, Lynsey S
dc.creator Hafferty, Jonathan D.
dc.creator Zeng, Yanni
dc.creator Adams, Mark James
dc.creator Clarke, Toni-Kim
dc.creator Porteous, David J.
dc.creator Nagy, Reka
dc.creator Hayward, Caroline
dc.creator Smith, Blair H.
dc.creator Murray, Alison D.
dc.creator Ryan, Niamh M.
dc.creator Evans, Kathryn L.
dc.creator Haley, Chris S.
dc.creator Deary, Ian J.
dc.creator Thomson, Pippa A.
dc.creator McIntosh, Andrew M.
dc.date 2017-12-13T10:12:05Z
dc.date 2017-12-13T10:12:05Z
dc.date 2017
dc.date.accessioned 2022-05-24T06:08:01Z
dc.date.available 2022-05-24T06:08:01Z
dc.identifier Howard , D M , Hall , L S , Hafferty , J D , Zeng , Y , Adams , M J , Clarke , T-K , Porteous , D J , Nagy , R , Hayward , C , Smith , B H , Murray , A D , Ryan , N M , Evans , K L , Haley , C S , Deary , I J , Thomson , P A & McIntosh , A M 2017 , ' Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank ' , Translational Psychiatry , vol. 7 , 1263 . https://doi.org/10.1038/s41398-017-0010-9
dc.identifier 2158-3188
dc.identifier PURE: 105630390
dc.identifier PURE UUID: 0892ac64-e165-45c6-a49e-91305465dcc9
dc.identifier Scopus: 85036531560
dc.identifier ORCID: /0000-0003-4915-4847/work/44018519
dc.identifier http://hdl.handle.net/2164/9774
dc.identifier https://doi.org/10.1038/s41398-017-0010-9
dc.identifier 7
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/117758
dc.description Generation Scotland received core funding from the Chief Scientist Office of the Scottish Government Health Directorate CZD/16/6 and the Scottish Funding Council HR03006. Genotyping of the GS:SFHS samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” (STRADL) Reference 104036/Z/14/Z. YZ acknowledges support from China Scholarship Council. IJD is supported by the Centre for Cognitive Ageing and Cognitive Epidemiology which is funded by the Medical Research Council and the Biotechnology and Biological Sciences Research Council (MR/K026992/1). AMMcI and T-KC acknowledges support from the Dr Mortimer and Theresa Sackler Foundation. We are grateful to all the families who took part, the general practitioners and the Scottish School of Primary Care for their help in recruiting them, and the whole Generation Scotland team, which includes interviewers, computer and laboratory technicians, clerical workers, research scientists, volunteers, managers, receptionists, healthcare assistants and nurses. Ethics approval for the study was given by the NHS Tayside committee on research ethics (reference 05/S1401/8)
dc.description Peer reviewed
dc.description Publisher PDF
dc.format application/pdf
dc.language eng
dc.relation Translational Psychiatry
dc.rights Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
dc.subject haplotype association analysis
dc.subject cognition
dc.subject intelligence
dc.subject IQ Generation Scotland
dc.subject UK Biobank
dc.subject English Longitudinal Study of Aging
dc.subject RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
dc.subject Chief Scientist Office (CSO)
dc.subject CZD/16/6
dc.subject Scottish Funding Council
dc.subject HR03006
dc.subject Medical Research Council (MRC)
dc.subject MR/K026992/1
dc.subject Wellcome Trust
dc.subject 104036/Z/14/Z
dc.subject Biotechnology and Biological Sciences Research Council (BBSRC)
dc.subject RC0321
dc.title Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank
dc.type Journal article


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