| dc.creator |
Celiz, Adam |
|
| dc.creator |
Smith, James |
|
| dc.creator |
Denning, Chris |
|
| dc.creator |
Alexander, Morgan |
|
| dc.date |
2015-06-04T15:07:35Z |
|
| dc.date |
2015-06-04T15:07:35Z |
|
| dc.date |
2015-06-08 |
|
| dc.date |
01/10/2010 - 01/06/2015 |
|
| dc.identifier |
https://rdmc.nottingham.ac.uk/handle/internal/15 |
|
| dc.identifier |
http://doi.org/10.17639/nott.12 |
|
| dc.description |
A scalable and cost-effective synthetic polymer substrate that supports robust expansion and subsequent multilineage differentiation of human pluripotent stem cells (hPSCs) with defined commercial media is presented. This substrate can be applied to common cultureware and used off-the-shelf after long-term storage. Expansion and differentiation of hPSCs are performed entirely on the polymeric surface, enabling the clinical potential of hPSC-derived cells to be realized.
Data presented herein includes time-of-flight secondary-ion mass spectrometry (ToF-SIMS), X-ray photoelectron spectroscopy (XPS), water contact angle (WCA) measurements, fluorescence microscopy, cell electrophysiology, nuclear magnetic resonance (NMR) spectroscopy, gel permeation chromatography (GPC).
Please note that this data set is in two parts, the second part of which can be found here: http://doi.org/10.17639/nott.16 |
|
| dc.language |
en |
|
| dc.publisher |
University of Nottingham |
|
| dc.relation |
http://onlinelibrary.wiley.com/doi/10.1002/adma.201501351/full |
|
| dc.relation |
http://doi.org/10.17639/nott.16 |
|
| dc.relation |
10.1002/adma.201501351 |
|
| dc.source |
See methods in manuscript (DOI: 10.1002/adma.201501351) |
|
| dc.subject |
Polymers in medicine |
|
| dc.subject |
Stem cells |
|
| dc.subject |
Human cell culture |
|
| dc.subject |
Cell differentiation |
|
| dc.subject |
Stem Cells |
|
| dc.subject |
Cell Culture Techniques |
|
| dc.subject |
Cell Differentiation |
|
| dc.subject |
Polymers |
|
| dc.subject |
high throughput; human pluripotent stem cells; materials discovery; polymer microarrays; stem cell differentiation; ToF-SIMS; XPS; WCA; Cell Microscopy; Electrophysiology; NMR and GPC datasets. |
|
| dc.subject |
JACS Subjects::Medicine and Dentistry::Clinical medicine |
|
| dc.subject |
JACS Subjects::Biological Sciences::Molecular biology, biophysics & biochemistry |
|
| dc.subject |
JACS Subjects::Biological Sciences::Biology::Cell biology |
|
| dc.subject |
JACS Subjects::Physical sciences::Chemistry::Analytical chemistry |
|
| dc.subject |
JACS Subjects::Physical sciences::Chemistry::Organic chemistry::Polymer chemistry |
|
| dc.subject |
JACS Subjects::Physical sciences::Materials science |
|
| dc.subject |
JACS Subjects::Engineering::Chemical, process & energy engineering::Chemical engineering::Biochemical engineering |
|
| dc.subject |
Library of Congress Subject Areas::T Technology::TP Chemical technology::TP1080 Polymers and polymer manufacture |
|
| dc.subject |
Library of Congress Subject Areas::R Medicine::R Medicine (General)::R855 Medical technology. Biomedical engineering. Electronics |
|
| dc.title |
Discovery of a novel polymer for human pluripotent stem cell expansion and multilineage differentiation - Supporting data 1 |
|
| dc.type |
dataset |
|