| dc.contributor |
Karad, Somnath |
|
| dc.contributor |
Panchal, Heena |
|
| dc.contributor |
Clarke, Christopher |
|
| dc.contributor |
Lewis, William |
|
| dc.creator |
Lam, Hon Wai |
|
| dc.date |
2018-05-22T15:15:54Z |
|
| dc.date |
2018-05-22T15:15:54Z |
|
| dc.date |
2018-05-22 |
|
| dc.identifier |
https://rdmc.nottingham.ac.uk/handle/internal/360 |
|
| dc.identifier |
http://doi.org/10.17639/nott.356 |
|
| dc.description |
Raw data for new compounds described in the paper: "Enantioselective Synthesis of Chiral Cyclopent-2-enones by Nickel-Catalyzed Desymmetrization of Malonate Esters". The enantioselective synthesis of highly functionalized chiral cyclopent-2-enones by the reaction of alkynyl malonate esters with arylboronic acids is described. These desymmetrizing arylative cyclizations are catalyzed by a chiral phosphinooxazoline–nickel complex, and cyclization is enabled by the reversible E/Z isomerization of alkenylnickel species. The general methodology is also applicable to the synthesis of 1,6-dihydropyridin-3(2H)-ones. |
|
| dc.language |
en |
|
| dc.publisher |
The University of Nottingham |
|
| dc.relation |
10.1002/anie.201805578 |
|
| dc.subject |
Chemicals -- Properties |
|
| dc.subject |
Enantioselective catalysis |
|
| dc.subject |
Asymmetric synthesis |
|
| dc.subject |
Chemical processes |
|
| dc.subject |
Raw data for new compounds described in the paper: "Enantioselective Synthesis of Chiral Cyclopent-2-enones by Nickel-Catalyzed Desymmetrization of Malonate Esters " |
|
| dc.subject |
Physical sciences::Chemistry::Physical chemistry |
|
| dc.subject |
Physical sciences::Chemistry::Organic chemistry |
|
| dc.subject |
Q Science::QD Chemistry::QD450 Physical and theoretical chemistry |
|
| dc.subject |
Q Science::QD Chemistry::QD241 Organic chemistry |
|
| dc.title |
Raw data for new compounds described in the paper: "Enantioselective synthesis of chiral cyclopent-2-enones by nickel-catalyzed desymmetrization of malonate esters" |
|
| dc.type |
dataset |
|