| dc.creator |
Dalal, HM |
|
| dc.creator |
Taylor, RS |
|
| dc.creator |
Jolly, K |
|
| dc.creator |
Davis, RC |
|
| dc.creator |
Doherty, P |
|
| dc.creator |
Miles, J |
|
| dc.creator |
van Lingen, R |
|
| dc.creator |
Warren, FC |
|
| dc.creator |
Green, C |
|
| dc.creator |
Wingham, J |
|
| dc.creator |
Greaves, C |
|
| dc.creator |
Sadler, S |
|
| dc.creator |
Hillsdon, M |
|
| dc.creator |
Abraham, C |
|
| dc.creator |
Britten, N |
|
| dc.creator |
Frost, J |
|
| dc.creator |
Singh, S |
|
| dc.creator |
Hayward, C |
|
| dc.creator |
Eyre, V |
|
| dc.creator |
Paul, K |
|
| dc.creator |
Lang, CC |
|
| dc.creator |
Smith, K |
|
| dc.date |
2018-11-22T13:24:49Z |
|
| dc.date |
2018-10-10 |
|
| dc.date |
2018-11-22T13:24:49Z |
|
| dc.date.accessioned |
2022-05-27T01:02:44Z |
|
| dc.date.available |
2022-05-27T01:02:44Z |
|
| dc.identifier |
Published online 10 October 2018 |
|
| dc.identifier |
10.1177/2047487318806358 |
|
| dc.identifier |
http://hdl.handle.net/10871/34871 |
|
| dc.identifier |
European Journal of Preventive Cardiology |
|
| dc.identifier.uri |
http://localhost:8080/xmlui/handle/CUHPOERS/241906 |
|
| dc.description |
This is the final version. Available on open access from SAGE Publications via the DOI in this record |
|
| dc.description |
Background Cardiac rehabilitation improves health-related quality of life (HRQoL) and reduces hospitalizations in patients with heart failure, but international uptake of cardiac rehabilitation for heart failure remains low. Design and methods The aim of this multicentre randomized trial was to compare the REACH-HF (Rehabilitation EnAblement in CHronicHeart Failure) intervention, a facilitated self-care and home-based cardiac rehabilitation programme to usual care for adults with heart failure with reduced ejection fraction (HFrEF). The study primary hypothesis was that the addition of the REACH-HF intervention to usual care would improve disease-specific HRQoL (Minnesota Living with Heart Failure questionnaire (MLHFQ)) at 12 months compared with usual care alone. Results The study recruited 216 participants, predominantly men (78%), with an average age of 70 years and mean left ventricular ejection fraction of 34%. Overall, 185 (86%) participants provided data for the primary outcome. At 12 months, there was a significant and clinically meaningful between-group difference in the MLHFQ score of -5.7 points (95% confidence interval -10.6 to -0.7) in favour of the REACH-HF intervention group ( p = 0.025). With the exception of patient self-care ( p < 0.001) there was no significant difference in other secondary outcomes, including clinical events ( p > 0.05) at follow-up compared with usual care. The mean cost of the REACH-HF intervention was £418 per participant. Conclusions The novel REACH-HF home-based facilitated intervention for HFrEF was clinically superior in disease-specific HRQoL at 12 months and offers an affordable alternative to traditional centre-based programmes to address current low cardiac rehabilitation uptake rates for heart failure. |
|
| dc.description |
The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: this work was supported by the United Kingdom's National Institute for Health Research (NIHR) Programme Grants for Applied Research (grant number RP-PG-1210-12004). RST and NB are part-funded by the National Institute for Health Research (NIHR) Collaboration for Peninsula Leadership in Applied Health Research and Care. KJ is part-funded by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLAHRC) West Midlands. SSingh is supported by NIHR CLARCH East Midlands. |
|
| dc.language |
en |
|
| dc.publisher |
SAGE Publications for European Society of Cardiology, European Association for Cardiovascular Prevention and Rehabilitation |
|
| dc.relation |
https://www.ncbi.nlm.nih.gov/pubmed/30304644 |
|
| dc.rights |
© The European Society of
Cardiology 2018. Open access. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
|
| dc.subject |
Cardiac rehabilitation |
|
| dc.subject |
health-related quality of life |
|
| dc.subject |
heart failure |
|
| dc.subject |
home-based |
|
| dc.subject |
randomized controlled trial |
|
| dc.subject |
self-management |
|
| dc.title |
The effects and costs of home-based rehabilitation for heart failure with reduced ejection fraction: The REACH-HF multicentre randomized controlled trial |
|
| dc.type |
Article |
|