Sangam: A Confluence of Knowledge Streams

Coordination of eukaryotic cilia and flagella

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dc.creator Wan, KY
dc.date 2018-11-22T14:39:30Z
dc.date 2018-11-21
dc.date 2018-11-22T14:39:30Z
dc.date.accessioned 2022-05-27T01:02:59Z
dc.date.available 2022-05-27T01:02:59Z
dc.identifier Published online 21 November 2018
dc.identifier 10.1042/EBC20180029
dc.identifier http://hdl.handle.net/10871/34877
dc.identifier 0071-1365
dc.identifier Essays in Biochemistry
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/241920
dc.description This is the final version. Available on open access from Portland Press via the DOI in this record
dc.description Propulsion by slender cellular appendages called cilia and flagella is an ancient means of locomotion. Unicellular organisms evolved myriad strategies to propel themselves in fluid environments, often involving significant differences in flagella number, localisation and modes of actuation. Remarkably, these appendages are highly conserved, occurring in many complex organisms such as humans, where they may be found generating physiological flows when attached to surfaces (e.g. airway epithelial cilia), or else conferring motility to male gametes (e.g. undulations of sperm flagella). Where multiple cilia arise, their movements are often observed to be highly coordinated. Here I review the two main mechanisms for motile cilia coordination, namely, intracellular and hydrodynamic, and discuss their relative importance in different ciliary systems.
dc.description This work was supported by a startup grant from the Living Systems Institute, University of Exeter, and a Springboard Award from the Academy of Medical Sciences.
dc.language en
dc.publisher Portland Press for Biochemical Society
dc.rights © 2018 The Author(s). This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND): https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.title Coordination of eukaryotic cilia and flagella
dc.type Article


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