Proteomic data associated to the cellular response of Desulfovibrio alaskensis G20 to Co(II) and or Ni(II). Experimental design: 1)Three different metal combinations were applied: single metal treatments, only Co(II) or Ni(II), and bimetallic (Co(II) and Ni(II) at equal concentrations). 2) Two different metal concentration levels (10 mg and 100 mg/L) 3) Two different incubation time points (2 and 20 h) to investigate the dynamics of proteins production.