Sangam: A Confluence of Knowledge Streams

Radiation Response Biomarkers for Individualised Cancer Treatments

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dc.contributor Badie, Christophe
dc.contributor Rutten, Eric Andreas
dc.date 2022-01-11T13:37:33Z
dc.date 2022-01-11T13:37:33Z
dc.date 2021
dc.date.accessioned 2023-02-18T19:29:47Z
dc.date.available 2023-02-18T19:29:47Z
dc.identifier ONIX_20220111_9783036516844_367
dc.identifier https://directory.doabooks.org/handle/20.500.12854/76632
dc.identifier https://mdpi.com/books/pdfview/book/4079
dc.identifier https://mdpi.com/books/pdfview/book/4079
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/249691
dc.description Personalised medicine is the next step in healthcare, especially when applied to genetically diverse diseases such as cancers. Naturally, a host of methods need to evolve alongside this, in order to allow the practice and implementation of individual treatment regimens. One of the major tasks for the development of personalised treatment of cancer is the identification and validation of a comprehensive, robust, and reliable panel of biomarkers that guide the clinicians to provide the best treatment to patients. This is indeed important with regards to radiotherapy; not only do biomarkers allow for the assessment of treatability, tumour response, and the radiosensitivity of healthy tissue of the treated patient. Furthermore, biomarkers should allow for the evaluation of the risks of developing adverse late effects as a result of radiotherapy such as second cancers and non-cancer effects, for example cardiovascular injury and cataract formation. Knowledge of all of these factors would allow for the development of a tailored radiation therapy regime. This Special Issue of the Journal of Personalised Medicine covers the topic of Radiation Response Biomarkers in the context of individualised cancer treatments, and offers an insight into some of the further evolution of radiation response biomarkers, their usefulness in guiding clinicians, and their application in radiation therapy.
dc.format image/jpeg
dc.language eng
dc.publisher MDPI - Multidisciplinary Digital Publishing Institute
dc.rights open access
dc.subject carbon-ion radiotherapy
dc.subject head-and-neck tumors
dc.subject squamous cell carcinoma
dc.subject radiosensitivity
dc.subject relative biological effectiveness
dc.subject lung cancer
dc.subject radiotherapy
dc.subject radiotherapy monitoring
dc.subject radiation-induced lung injury
dc.subject RILI
dc.subject pneumonitis
dc.subject radiation-induced lung fibrosis
dc.subject RILF
dc.subject circulating biomarkers
dc.subject microRNA
dc.subject micronuclei
dc.subject uterine cervical cancer
dc.subject cGAS
dc.subject STING
dc.subject abscopal effect
dc.subject immunotherapy
dc.subject PBMCS
dc.subject micronucleus assay
dc.subject biological dosimetry
dc.subject human blood
dc.subject genotoxicity tests
dc.subject ionizing radiation
dc.subject biomarkers
dc.subject dicentric assay
dc.subject gamma H2AX foci assay
dc.subject health surveillance analyses
dc.subject clonogenic assays
dc.subject methods
dc.subject plating
dc.subject cancer
dc.subject radiation
dc.subject head and neck cancer
dc.subject exosomes
dc.subject serum
dc.subject metabolomics
dc.subject GC/MS
dc.subject biodosimetry
dc.subject chromosome aberrations
dc.subject normal tissue toxicity
dc.subject predictive tests
dc.subject normal tissue
dc.subject biomarker
dc.subject protein
dc.subject immune infiltrate
dc.subject stroma
dc.subject tumour microenvironment
dc.subject proteomics
dc.subject telomeres
dc.subject chromosomal instability
dc.subject inversions
dc.subject prostate cancer
dc.subject IMRT
dc.subject machine learning
dc.subject individual radiosensitivity
dc.subject late effects
dc.subject personalized medicine
dc.subject liquid biopsy
dc.subject circulating tumour cells
dc.subject extracellular vesicles
dc.subject microRNAs
dc.subject immune system
dc.subject inflammation
dc.subject n/a
dc.subject bic Book Industry Communication::M Medicine
dc.title Radiation Response Biomarkers for Individualised Cancer Treatments
dc.resourceType book
dc.alternateIdentifier 9783036516844
dc.alternateIdentifier 9783036516837
dc.alternateIdentifier 10.3390/books978-3-0365-1683-7
dc.licenseCondition Attribution 4.0 International
dc.identifierdoi 10.3390/books978-3-0365-1683-7
dc.relationisPublishedBy 46cabcaa-dd94-4bfe-87b4-55023c1b36d0
dc.relationisbn 9783036516844
dc.relationisbn 9783036516837
dc.pages 231
dc.placepublication Basel, Switzerland


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