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Real-time, sensitive electrical detection of Cryptosporidium parvum oocysts based on chemical vapor deposition-grown graphene

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dc.contributor Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
dc.contributor Palacios, Tomas
dc.contributor Kong, Jing
dc.creator It Wong, Jen
dc.creator Wang, Lu
dc.creator Shi, Yumeng
dc.creator Palacios, Tomas
dc.creator Kong, Jing
dc.creator Dong, Xiaochen
dc.creator Ying Yang, Hui
dc.date 2014-05-28T15:25:59Z
dc.date 2014-05-28T15:25:59Z
dc.date 2014-02
dc.date 2013-12
dc.date.accessioned 2023-03-01T18:10:08Z
dc.date.available 2023-03-01T18:10:08Z
dc.identifier 0003-6951
dc.identifier 1077-3118
dc.identifier http://hdl.handle.net/1721.1/87553
dc.identifier It Wong, Jen, Lu Wang, Yumeng Shi, Tomás Palacios, Jing Kong, Xiaochen Dong, and Hui Ying Yang. “Real-Time, Sensitive Electrical Detection of Cryptosporidium Parvum Oocysts Based on Chemical Vapor Deposition-Grown Graphene.” Appl. Phys. Lett. 104, no. 6 (February 10, 2014): 063705. © 2014 AIP Publishing.
dc.identifier https://orcid.org/0000-0003-0551-1208
dc.identifier https://orcid.org/0000-0002-2190-563X
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/279008
dc.description Cryptosporidium parvum is a common intestinal parasitic protozoan that causes gastroenteritis in man and animals. It poses high risks to drinking water supply because of its ubiquitous distribution in water and their oocysts are resistant to harsh environment conditions. In this work, we demonstrated the use of large-size chemical vapor deposition (CVD) grown graphene films configured as field-effect device for rapid electrical detection of Cryptosporidium parvum oocysts (Cp. oocysts). The presence of Cp. oocysts causes the change in the transport characteristics of the antibody-functionalized graphene device, which can be measured in terms of the dependence of the drain current on the sweep of the gate voltage or the real-time drain current data under a constant gate voltage. The high sensor sensitivity of 25 oocysts per milliliter solution and good specificity were evaluated, indicating it a promising candidate for detecting waterborne pathogens in water quality control.
dc.description Singapore University of Technology and Design (Zhe Jiang University joint pilot research project (SUTD-ZJU/PILOT/01/2011))
dc.description Jiangsu Province (China) (Funds for Distinguished Young Scholars (SBK201310284))
dc.description National Natural Science Foundation (China) (1275076)
dc.description National Natural Science Foundation (China) (61328401)
dc.description China. Ministry of Education (212058)
dc.description Specialized Research Fund for the Doctoral Program of Higher Education (China) (20123223110008)
dc.format application/pdf
dc.language en_US
dc.publisher American Institute of Physics
dc.relation http://dx.doi.org/10.1063/1.4864154
dc.relation Applied Physics Letters
dc.rights Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.source MIT web domain
dc.title Real-time, sensitive electrical detection of Cryptosporidium parvum oocysts based on chemical vapor deposition-grown graphene
dc.type Article
dc.type http://purl.org/eprint/type/JournalArticle


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