A comparison of the relative yields of Υ resonances in the μ[superscript +]μ[superscript -] decay channel in Pb-Pb and pp collisions at a center-of-mass energy per nucleon pair of 2.76 TeV is performed with data collected with the CMS detector at the LHC. Using muons of transverse momentum above 4 GeV/c and pseudorapidity below 2.4, the double ratio of the Υ(2S) and Υ(3S) excited states to the Υ(1S) ground state in Pb-Pb and pp collisions, [Υ(2S+3S)/Υ(1S)][subscript Pb-Pb]/[Υ(2S+3S)/Υ(1S)][subscript pp], is found to be 0.31[subscript -0.15][superscript +0.19](stat)±0.03(syst). The probability to obtain the measured value, or lower, if the true double ratio is unity, is calculated to be less than 1%.