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dc.creator Aylward, Frank O.
dc.creator Moniruzzaman, Mohammad
dc.date 2022-08-11T13:33:21Z
dc.date 2022-08-11T13:33:21Z
dc.date 2022-07-30
dc.date 2022-08-11T11:49:53Z
dc.date.accessioned 2023-03-01T18:53:13Z
dc.date.available 2023-03-01T18:53:13Z
dc.identifier Aylward, F.O.; Moniruzzaman, M. Viral Complexity. Biomolecules 2022, 12, 1061.
dc.identifier http://hdl.handle.net/10919/111508
dc.identifier https://doi.org/10.3390/biom12081061
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/281701
dc.description Although traditionally viewed as streamlined and simple, discoveries over the last century have revealed that viruses can exhibit surprisingly complex physical structures, genomic organization, ecological interactions, and evolutionary histories. Viruses can have physical dimensions and genome lengths that exceed many cellular lineages, and their infection strategies can involve a remarkable level of physiological remodeling of their host cells. Virus–virus communication and widespread forms of hyperparasitism have been shown to be common in the virosphere, demonstrating that dynamic ecological interactions often shape their success. And the evolutionary histories of viruses are often fraught with complexities, with chimeric genomes including genes derived from numerous distinct sources or evolved de novo. Here we will discuss many aspects of this viral complexity, with particular emphasis on large DNA viruses, and provide an outlook for future research.
dc.description Published version
dc.format application/pdf
dc.format application/pdf
dc.language en
dc.publisher MDPI
dc.rights Creative Commons Attribution 4.0 International
dc.rights http://creativecommons.org/licenses/by/4.0/
dc.title Viral Complexity
dc.title Biomolecules
dc.type Article - Refereed
dc.type Text


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