Sangam: A Confluence of Knowledge Streams

Diagnosis and Surgical Treatment of Drug-Resistant Epilepsy

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dc.creator Anyanwu, Chinekwu
dc.creator Motamedi, Gholam K.
dc.date 2019-04-01T11:58:24Z
dc.date 2019-04-01T11:58:24Z
dc.date 2018-03-21
dc.date 2019-03-29T19:40:00Z
dc.date.accessioned 2023-03-01T18:54:33Z
dc.date.available 2023-03-01T18:54:33Z
dc.identifier Anyanwu, C.; Motamedi, G.K. Diagnosis and Surgical Treatment of Drug-Resistant Epilepsy. Brain Sci. 2018, 8, 49.
dc.identifier http://hdl.handle.net/10919/88762
dc.identifier https://doi.org/10.3390/brainsci8040049
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/281840
dc.description Despite appropriate trials of at least two antiepileptic drugs, about a third of patients with epilepsy remain drug resistant (intractable; refractory). Epilepsy surgery offers a potential cure or significant improvement to those with focal onset drug-resistant seizures. Unfortunately, epilepsy surgery is still underutilized which might be in part because of the complexity of presurgical evaluation. This process includes classifying the seizure type, lateralizing and localizing the seizure onset focus (epileptogenic zone), confirming the safety of the prospective brain surgery in terms of potential neurocognitive deficits (language and memory functions), before devising a surgical plan. Each one of the above steps requires special tests. In this paper, we have reviewed the process of presurgical evaluation in patients with drug-resistant focal onset epilepsy.
dc.description Published version
dc.format application/pdf
dc.format application/pdf
dc.language en
dc.publisher MDPI
dc.rights Creative Commons Attribution 4.0 International
dc.rights http://creativecommons.org/licenses/by/4.0/
dc.subject medically intractable epilepsy
dc.subject EEG
dc.subject epilepsy surgery
dc.subject MRI
dc.subject epilepsy
dc.subject seizures
dc.title Diagnosis and Surgical Treatment of Drug-Resistant Epilepsy
dc.title Brain Science
dc.type Article - Refereed
dc.type Text


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