Sangam: A Confluence of Knowledge Streams

Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices

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dc.contributor David E. Hardt.
dc.contributor Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
dc.contributor Massachusetts Institute of Technology. Department of Mechanical Engineering
dc.creator Hum, Philip W. (Philip Wing-Jung)
dc.date 2007-03-12T17:50:07Z
dc.date 2007-03-12T17:50:07Z
dc.date 2006
dc.date 2006
dc.date.accessioned 2022-05-04T06:27:23Z
dc.date.available 2022-05-04T06:27:23Z
dc.identifier http://hdl.handle.net/1721.1/36748
dc.identifier 78263832
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/3000
dc.description Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006.
dc.description Includes bibliographical references (leaves 54-56).
dc.description Discussion of the current manufacturing process of polydimethylsiloxane (PDMS) parts and the emergence of PDMS use in biomedical microfluidic devices addresses the need to develop large scale manufacturing processes for the fabrication of said devices. Casting PDMS parts is found to be the best mass production process after evaluating several different production methods. Automation of the manufacturing process is introduced as a solution to the need for mass production. Changing variables within the production process and its effects are also discussed with the recommendation being made for using low viscosity pre-cured PDMS, high temperature curing and high vacuum degassing techniques to produce high quality parts at high production rates. The further development of producing two-sided PDMS parts is recommended by investigating the usage of a non-closed aspect limited casting process.
dc.description by Philip W. Hum.
dc.description S.B.
dc.format 56 leaves
dc.format application/pdf
dc.language eng
dc.publisher Massachusetts Institute of Technology
dc.rights M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
dc.rights http://dspace.mit.edu/handle/1721.1/7582
dc.subject Mechanical Engineering.
dc.title Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices
dc.type Thesis


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