Sangam: A Confluence of Knowledge Streams

The Potential for Acupuncture to Mediate Hippocampal Apoptosis: A Systematic Review

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dc.contributor Koh, Yunsuk
dc.contributor Baylor University.
dc.contributor Health Science Studies.
dc.contributor honors college
dc.creator Marsheck, Hana
dc.date 2019-12-19T17:15:25Z
dc.date 2019-12-19T17:15:25Z
dc.date 2019-12-09
dc.date 2019-12-19
dc.date.accessioned 2022-05-18T12:28:54Z
dc.date.available 2022-05-18T12:28:54Z
dc.identifier https://hdl.handle.net/2104/10789
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/31693
dc.description Apoptosis is programmed cell death that can be maladaptive when not properly regulated, especially when it occurs in the hippocampus. The exact mechanisms for apoptotic malfunctioning are yet to be fully understood. Acupuncture has seen a recent rise in western medicine and is used to treat various blood flow related conditions such as strokes or ischemia. The exact mechanisms for acupuncture are also still unknown. This systematic review evaluated the potential for acupuncture to help mediate hippocampal apoptosis. A search was conducted through PubMed, Scopus, and WebofScience using the keywords “hippocampus,” “apoptosis,” and “acupuncture” and found 37 qualified articles from January 2009 to March 2019. All of the articles supported acupuncture decreasing the incidence of hippocampal apoptosis. The most frequently suggested mechanism was decreased BAX expression and increased BCL-2 expression, often in the CA1 region of the hippocampus; although, it was only seen in about 1/3 of the articles. While no exact mechanism is understood within current literature, acupuncture does indeed have the potential to mediate hippocampal apoptosis.
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dc.rights Baylor University projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact libraryquestions@baylor.edu for inquiries about permission.
dc.rights Worldwide access
dc.title The Potential for Acupuncture to Mediate Hippocampal Apoptosis: A Systematic Review
dc.type Thesis


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